Recombinant Human B- and T-Lymphocyte Attenuator/BTLA/CD272 (C-6His)
Produktgrößen
10 µg
£477,00
32-7511-10UG
50 µg
£625,00
32-7511-50UG
Über dieses Produkt
- SKU:
- 32-7511
- Weitere Details:
- Source: Human Cells. MW :14.79kD. Recombinant Human BTLA is produced by our Mammalian expression system and the target gene encoding Lys31-Leu150 is expressed with a 6His tag at the C-terminus. B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells; and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4; BTLA interacts with a B7 homolog; B7H4. However; unlike PD-1 and CTLA-4; BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R); not just the B7 family of cell surface receptors. BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response. BTLA also is a ligand for tumor necrosis factor (receptor) superfamily; member 14 (TNFRSF14); also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php