Recombinant Human Serpin F1/PEDF(C-6His)
Produktgrößen
10 µg
£514,00
32-7489-10UG
50 µg
£737,00
32-7489-50UG
Über dieses Produkt
- SKU:
- 32-7489
- Weitere Details:
- Source: Human Cells. MW :45.42kD. Recombinant Human Serpin F1/PEDF is produced by our Mammalian expression system and the target gene encoding Gln20-Pro418 is expressed with a 6His tag at the C-terminus. Serpin F1 is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain; three major beta-sheets; and ten alpha-helices. As protease inhibitors; serpins have an array of functions including regulating blood clotting; the complement pathway; extracellular matrix remodeling; and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance; they may also regulate blood pressure; angiogenesis; or act as storage/transport proteins. Serpin F1 is a new promising approach for the treatment of osteosarcoma and has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. The human serpin superfamily consists of at least 35 members that target not only serine proteases; but also selected cysteine proteases and non-protease proteins. Levels of the natural ocular anti-angiogenic factor SentrinF1 (PEDF) is associated with proliferative retinopathy.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php