Recombinant Human Semaphorin-5A/SEMA5A (C-6His)
Produktgrößen
10 µg
£514,00
32-7452-10UG
50 µg
£737,00
32-7452-50UG
Über dieses Produkt
- SKU:
- 32-7452
- Weitere Details:
- Source: Human Cells. MW :84.71kD. Recombinant Human Semaphorin 5A is produced by our Mammalian expression system and the target gene encoding Glu23-Thr765 is expressed with a 6His tag at the C-terminus. Semaphorin-5A (SEMA5A) is a member of the Semaphorin family of axon guidance molecules. SEMA5A is a 140 kDa protein. Class 5 Semaphorins are type I transmembrane glycoproteins with an N- terminal Sema domain and multiple juxtamembrane type 1 Thrombospondin (TSP) repeats within their extracellular domains. SEMA5A is expressed in neuroepithelial cells surrounding retinal axons; oligodendrocytes; the base of limb buds; the mesoderm surrounding cranial vessels ; and the cardiac atrial septum and endocardial cushions; Human SEMA5A cDNA encodes a signal sequence; a extracellular domain (ECD); a transmembrane sequence and an cytoplasmic portion. SEMA5A mutations have been implicated in the genetic syndrome;cri-du-chat;while some polymorphisms may increase risk for neurodegenerative diseases such as Parkinson. The expression of SEMA5A may be upregulated in metastatic cancer cells and downregulated in autism.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php