Recombinant Human Cadherin-6/K-Cadherin/CDH6 (C-6His)
Produktgrößen
10 µg
£488,00
32-7388-10UG
50 µg
£636,00
32-7388-50UG
Über dieses Produkt
- SKU:
- 32-7388
- Weitere Details:
- Source: Human Cells. MW :67.43kD. Recombinant Human Cadherin-6 is produced by our Mammalian expression system and the target gene encoding Thr22-Ala615 is expressed with a 6His tag at the C-terminus. Cadherin-6 (CDH6) is a type-II classic cadherin cell-cell adhesion molecules; which are expressed in graded or areal patterns; as well as layer-specific patterns; in the cortical plate. Human Cadherin-6 is synthesized as a 790 aa type I transmembrane glycoprotein that contains a 18 aa signal peptide; a 35 aa propeptide; a 562 aa extracellular region; a 21 aa transmembrane segment; and a 154 aa cytoplasmic domain. There are five cadherin domains of approximately 110 aa each in the extracellular region. Cadherin-6 has high expression in kidney; brain; and cerebellum; and may contribute to the formation of the segmental structure of the early brain; as well as the development of renal proximal tubules. Weak expression is also detected in lung; pancreas; gastric mucosa and cytotrophoblasts. As a classic cadherin; Cadherin-6 will form homodimers and promote intercellular adhesion with itself and; possibly; Cadherin-9 and -14.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php