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Proteine und Peptide

Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 (C-6His)

Produktgrößen
10 µg
£612,00
32-7375-10UG
50 µg
£919,00
32-7375-50UG
Über dieses Produkt
SKU:
32-7375
Weitere Details:
Source: Human Cells. MW :84.63kD. Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a 6His tag at the C-terminus. Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family; the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase; ACE-2 converts angiotensin I to angiotensin 1-9; and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis; kidney and heart; in colon; small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Versandbedingungen:
Dry Ice
Lagerbedingungen:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins