Recombinant Human TWSG1/TSG (C-6His)
Produktgrößen
10 µg
£526,00
32-7357-10UG
50 µg
£774,00
32-7357-50UG
Über dieses Produkt
- SKU:
- 32-7357
- Weitere Details:
- Source: Human Cells. MW :23.18kD. Recombinant Human TWSG1 is produced by our Mammalian expression system and the target gene encoding Cys26-Phe223 is expressed with a 6His tag at the C-terminus. Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide and a 198 aa mature chain. TWSG1 may be involved in dorsoventral axis formation. TWSG1 seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs; thereby preventing BMPs from binding to their receptors.TWSG1 can inhibit BMP activity by binding directly to BMP proteins; and can act the anti-BMP function; partly mediated by cleavage and degradation of CHRD; which releases BMPs from ternary complexes. TWSG1 may be an important modulator of BMP-regulated cartilage development; chondrocyte differentiation and thymocyte development.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php