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Proteine und Peptide

Recombinant Human Legumain/Asparaginyl Endopeptidase (C-6His)

Produktgrößen
10 µg
£612,00
32-7340-10UG
50 µg
£919,00
32-7340-50UG
Über dieses Produkt
SKU:
32-7340
Weitere Details:
Source: Human Cells. MW :48.72kD. Recombinant Human Legumain is produced by our Mammalian expression system and the target gene encoding Ile18-Tyr433 is expressed with a 6His tag at the C-terminus. Legumain is a lysosomal cysteine protease which is a member of the peptidase C13 family. Though it is found in many tissues; it is highly expressed in the kidney; heart; and placenta. Legumain has a strict specificity for hydrolysis of asparaginyl bonds and can also cleave aspartyl bonds slowly; especially under acidic conditions. Over-expression Legumain in tumors is significant for invasion and metastasis. In addition; Legumain may be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system and negative regulation of neuron apoptosis.
Versandbedingungen:
Dry Ice
Lagerbedingungen:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins