Recombinant Human Vinculin
Produktgrößen
10 µg
£562,00
32-7242-10UG
50 µg
£869,00
32-7242-50UG
Über dieses Produkt
- SKU:
- 32-7242
- Weitere Details:
- Source: E.coli. MW :117kD. Recombinant Human Vinculin is produced by our E.coli expression system and the target gene encoding Pro2-Gln1066 is expressed. Vinculin is a focal adhesion and cytoskeletal protein that distributed mainly at cell-cell junctions and cell-extracellular matrix (ECM) adhesion that belongs to the Vinculin/a-Catenin family. Vinculin is an Actin-binding protein and component of the Actin-Linking Functional module that senses and feels the mechanical properties of the extracellular environment. Vinculin is also a key factor that couples; transmits; transduces; and regulates mechanical force between the cytoskeleton and adhesion receptors. Vinculin generally forms two structural states; an open (active) and closed (inactive) state; which are controlled by conformational interaction(s) between the head and tail domains. Vinculin is involved in the mechano-chemical signal transmission of cells by binding to a variety of focal adhesion or cytoskeletal proteins; and plays important roles in cell adhesion; extension; motion; proliferation and survival.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php