Recombinant Human Xaa-Pro Aminopeptidase 1/XPNPEP1 (C-6His)
Produktgrößen
10 µg
£612,00
32-7171-10UG
50 µg
£919,00
32-7171-50UG
Über dieses Produkt
- SKU:
- 32-7171
- Weitere Details:
- Source: E.coli. MW :70.6kD. Recombinant Human Aminopeptidase P1 is produced by our E.coli expression system and the target gene encoding Pro2-His623 is expressed with a 6His tag at the C-terminus. X-Prolyl Aminopeptidase (XPNPEP1) is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline; it has been suggested that X-Prolyl Aminopeptidase is important in the maturation and degradation of peptide hormones; neuropeptides; and tachykinins; as well as in the digestion of otherwise resistant dietary protein fragments; thereby complementing the pancreatic peptidases. X-Prolyl Aminopeptidase is a member of the M24 family of metalloproteases; which also contains methionine aminopeptidases; X-Pro dipeptidase; aminopeptidase P2; aminopeptidase P homolog; proliferation-associated protein 1; and suppressor of Ty homolog or chromatin-specific transcription elongation factor large subunit. It is a soluble enzyme; in contrast to the GPI-anchored Aminopeptidase P2 encoded by XPNPEP2. Deficiency of X-Prolyl Aminopeptidase results in excretion of large amounts of imino-oligopeptides in urine. Human Aminopeptidase P1 is widely expressed. The amino acid sequence of human X-Prolyl Aminopeptidase is 99%; 97%; 95%; 74% and 73% identical to that of canine; bovine; mouse/rat; Xenopus and zebrafish; respectively.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:download_pdf.php