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Proteine und Peptide

Recombinant Human Ubiquitin-Conjugating Enzyme E2 H/UBE2H (N-GST)

Produktgrößen
10 µg
£484,00
32-7163-10UG
50 µg
£532,00
32-7163-50UG
Über dieses Produkt
SKU:
32-7163
Weitere Details:
Source: E.coli. MW :47kD. Recombinant Human Ubiquitin-Conjugating Enzyme E2 H is produced by our E.coli expression system and the target gene encoding Met1-Leu183 is expressed with a GST tag at the N-terminus. Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes; or E1s; ubiquitin-conjugating enzymes; or E2s; and ubiquitin-protein ligases; or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6; which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.
Versandbedingungen:
Dry Ice
Lagerbedingungen:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins