Recombinant Human Microtubule-Associated Protein Tau/MAPT-D/Tau-D (C-6His)
Produktgrößen
10 µg
£514,00
32-7155-10UG
50 µg
£737,00
32-7155-50UG
Über dieses Produkt
- SKU:
- 32-7155
- Weitere Details:
- Source: E.coli. MW :15.37kD. Recombinant Human Microtubule-Associated Protein Tau-D is produced by our E.coli expression system and the target gene encoding Gln249-Gln381 is expressed with a 6His tag at the C-terminus. Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere; but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components; suggesting that tau acts as a linker protein. When tau is defective; and no longer stabilize microtubules properly; it can result in dementias such as Alzheimer's disease and other tauopathies.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php