Recombinant Human Bcl-2-Llike Protein 2/BCL2L2 (C-6His)
Produktgrößen
10 µg
£538,00
32-7090-10UG
50 µg
£719,00
32-7090-50UG
Über dieses Produkt
- SKU:
- 32-7090
- Weitere Details:
- Source: E.coli. MW :19.87kD. Recombinant Human B Cell Lymphoma is produced by our E.coli expression system and the target gene encoding Ala2-Thr172 is expressed with a 6His tag at the C-terminus. Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain; spinal cord; testis; pancreas; heart; spleen; and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs; BH1; BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore; BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php