FGFR2 Human; (22-289)
Produktgrößen
2 µg
£452,00
32-6973-2UG
10 µg
£528,00
32-6973-10UG
Über dieses Produkt
- SKU:
- 32-6973
- Zusätzliche Namen:
- EC 2.7.10; FGFR-2; BFR-1; CD332; BBDS; CEK3; ECT1; TK14; TK25; CFD1; KSAM; JWS; Fibroblast Growth Factor Receptor 2; Keratinocyte Growth Factor Receptor; Bacteria-Expressed Kinase; EC 2.7.10.1; K-SAM; KGFR; BEK; Protein Tyrosine Kinase; Receptor Like 14; BEK Fibroblast Growth Factor Receptor; Crani
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Fibroblast Growth Factors (FGFs) comprise a family of at least 18 structurally related proteins that take part in a multitude of physiological and pathological cellular processes; includingdifferentiation; cell growth; angiogenesis; wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family if type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. 4 different genes encoding related FGF receptors. Multiple forms of FGFR-1 to -3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGFR-1 and -2 results in receptors containing all three Ig domains; referred to as the alpha isoform; or only IgII and IgIII. Only the alpha isoform has been identified for FGFR-3 and FGFR-4. Additional splicing events for FGFR-1 to -3; involving the C-terminal half of the IgIII domain encoded by 2 mutually exclusive alternative exons; generate FGF receptors with alternative IgIII domains (IIIb and IIIc). A IIIa isoform which is a secreted FGF binding protein containing only the N-terminal half of the IgIII domain plus some intron sequences has also been reported for FGFR-1.FGFR2 produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 507 amino acids (22-289a.a.) and having a molecular mass of 56.8kDa. FGFR2 is expressed with a 239 amino acid hIgG-His-Tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php