ErbB3 Human; sf9
Produktgrößen
2 µg
£452,00
32-6966-2UG
10 µg
£528,00
32-6966-10UG
Über dieses Produkt
- SKU:
- 32-6966
- Zusätzliche Namen:
- Tyrosine Kinase ErbB-3; sf9; ErbB3 sf9; Receptor tyrosine-protein kinase erbB-3; ERBB3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; HER3; Receptor tyrosine-protein kinase erbB-3 isoform; c-erbB-3; ErbB-3; erbB3-S; LCCS2; MDA-BF-1; p180-ErbB3; p45-sErbB3; p
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.ErbB3; also called Her3 (human epidermal growth factor receptor 3); is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors. Among ErbB family members; ErbB3 is unique in that it contains a defective kinase domain. ErbB3 is expressed in keratinocytes; melanocytes; skeletal muscle cells; embryonic myoblasts and Schwann cells. Monomeric ErbB3 serves as a low affinity receptor for the heregulins (HRG). ErbB3 can induce specific antibody production in vivo; hence to inhibit tumor cell growth. ErbB-3 can be used to treat early; medium and advanced or post-operative breast cancer with over-expression of ErbB2. According to its mechanism of action; ErbB3 is classified as a therapeutic for cancer.ErbB3 Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 863 amino acids (20-643 a.a.) and having a molecular mass of 95.6kDa (Migrates at 100-150kDa on SDS-PAGE under reducing conditions).ErbB3 is expressed with a 239 amino acid hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php