ErbB2 Human; Sf9
Produktgrößen
1 µg
£452,00
32-6965-1UG
5 µg
£528,00
32-6965-5UG
Über dieses Produkt
- SKU:
- 32-6965
- Zusätzliche Namen:
- Receptor tyrosine-protein kinase erbB-2; EC 2.7.10.1; p185erbB2; C-erbB-2; NEU proto-oncogene; Tyrosine kinase-type cell surface receptor HER2; MLN 19; CD340 antigen; NEU; NGL; HER2; TKR1; HER-2; c-erb B2; HER-2/neu.
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered clear solution.HER-2/neu (erbB-2) encodes an 185-kDa orphan receptor tyrosine kinase that is constitutively active as a dimer and displays potent oncogenic activity when overexpressed. Herstatin; as the product of alternative HER-2 transcript; retains intron 8.The herstatin mRNA is expressed in normal human fetal kidney and liver; but is at reduced levels relative to p185HER-2 mRNA in carcinoma cells that contain an amplified HER-2 gene. Herstatin appears to be an inhibitor of p185HER-2; because it disrupts dimers; reduces tyrosine phosphorylation of p185; and inhibits the anchorage-independent growth of transformed cells that overexpress HER-2.ErbB2 Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 638 amino acids (23-652) and having a molecular mass of 70.4kDa (Molecular size on SDS-PAGE will appear at approximately 70-100kDa). ErbB2 is fused to 8 amino acid IgG His-Tag at C-terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 85.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php