AKT1 Human; Sf9
Produktgrößen
2 µg
£452,00
32-6956-2UG
10 µg
£528,00
32-6956-10UG
Über dieses Produkt
- SKU:
- 32-6956
- Zusätzliche Namen:
- V-Akt Murine Thymoma Viral Oncogene Homolog 1; Protein Kinase B Alpha; Proto-Oncogene C-Akt; RAC-PK-Alpha; EC 2.7.11.1; PKB Alpha; CWS6; PKB; RAC; RAC-Alpha Serine/Threonine-Protein Kinase; Rac Protein Kinase Alpha; Protein Kinase B; PKB-ALPHA; RAC-ALPHA; EC 2.7.11; AKT1m; PRKBA; AKT; RAC-alpha ser
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile filtered colorless solution.Akt1; also known as Akt or else protein kinase B (PKB) is an important molecule in mammaliancellular signaling. In humans; there are three genes in the "Akt family": Akt1; Akt2; and Akt3. Moreover; these enzymes are members of the serine/threonine-specific protein kinase family (EC2.7.11.1). Akt1 is involved in cellular survival pathways; by inhibiting apoptoticprocesses. Akt1 is also able to induce protein synthesis pathways; and is therefore a key signaling protein in the cellular pathways which lead to skeletal muscle hypertrophy; and general tissue growth. Since it can block apoptosis; and thereby promote cell survival; Akt1 has been implicated as a most important factor in numerous types of cancer. Akt (now also called Akt1) was at first identified as the oncogenein the transforming retrovirus; AKT8.AKT1 produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 488 amino acids (1-480a.a.) and having a molecular mass of 56.7kDa. (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). AKT1 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php