TGM2 Mouse
Produktgrößen
5 µg
£452,00
32-6920-5UG
20 µg
£528,00
32-6920-20UG
Über dieses Produkt
- SKU:
- 32-6920
- Zusätzliche Namen:
- Protein-glutamine gamma-glutamyltransferase 2; G[a]h; TG2; TGase2; tTG; tTGas; Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; Transglutaminase C.
- Weitere Details:
- Source: E.coli.Sterile Filtered colorless solution.Celiac disease is an enteropathy that is characterized by intestinal lesions of variable severity. Tissue-type transglutaminase (tTG) is believed to be the predominant autoantigen for celiac disease and the corresponding autoantibodies show higher sensitivity and specificity than anti-gliadin antibodies. Highly pure recombinant human tTG is now available to replace the traditionally used tTG fraction from guinea pig.Tissue-type transglutaminase antigens have been specifically modified for improved handling: exchange of an active site amino acid eliminates the protein cross-linking activity of the enzyme; while maintaining the native three-dimensional structure and the enzyme's secondary GTPase activity. This engineering assures reproducible properties of the antigen preparations through the absence of variable and ill-defined covalent aggregates of tTG antigen and host cell proteins.TGM2 Mouse Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 709 amino acids (1-686 a.a) and having a molecular mass of 79.4kDa.TGM2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 85% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php