PDIA3 Mouse
Produktgrößen
2 µg
£452,00
32-6874-2UG
10 µg
£528,00
32-6874-10UG
Über dieses Produkt
- SKU:
- 32-6874
- Zusätzliche Namen:
- ERp57; ERp60; ERp61; GRP57; GRP58; HsT17083; P58; PI-PLC; ER60; Protein disulfide-isomerase A3; Disulfide isomerase ER-60; Endoplasmic reticulum resident protein 60; ER protein 60; 58 kDa microsomal protein; Endoplasmic reticulum resident protein 57; ER protein 57; 58 kDa glucose-regulated protein;
- Weitere Details:
- Source: Escherichia Coli.Sterile filtered colourless solution.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 has protein disulfide isomerase activity. Complexes of lectins and PDIA3 mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. PDIA3 is expressed in the lumbar spinal cord from rats submitted to peripheral lesion during neonatal period. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1); which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.PDIA3 Mouse Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 505 amino acids (25-505 a.a) and having a molecular mass of 56.8kDa. PDIA3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php