NNMT Human; Active
Produktgrößen
2 µg
£452,00
32-6861-2UG
10 µg
£528,00
32-6861-10UG
Über dieses Produkt
- SKU:
- 32-6861
- Zusätzliche Namen:
- Nicotinamide N-methyltransferase; EC 2.1.1.1; NNMT.
- Weitere Details:
- Source: Escherichia Coli.Sterile filtered colorless solution.NNMT is part of the family of transferases; especially those transferring one-carbon group methyltransferases. NNMT is mostly expressed in the liver; and a lower expression is seen in the kidney; lung; skeletal muscle; placenta and heart. NNMT catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is significant for biotransformation of many drugs and xenobiotic compounds. NNMT is accountable for the enzymatic activity which uses S-adenosyl methionine as the methyl donor. NNMT expression is related with tumor stage and DFS time in hepatocellular carcinoma cases. NNMT is a good candidate as a tumor marker of various kinds of cancers. NNMT serum levels have significance in the premature detection and in the management of patients with colorectal cancer.NNMT Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 284 amino acids (1-264 a.a) and having a molecular mass of 37.7kDa.NNMT is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php