MMP1 (24-207) Human
Produktgrößen
2 µg
£452,00
32-6847-2UG
10 µg
£528,00
32-6847-10UG
Über dieses Produkt
- SKU:
- 32-6847
- Zusätzliche Namen:
- nterstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1; MMP1; CLG; CLGN.
- Weitere Details:
- Source: HEK293 Cells.Filtered White lyophilized (freeze-dried) powder.MMP-1 (interstitial collagenase) can break down a wide range of substrates including types I; II; III; VII; VIII; and X collagens as well as L-Selectin; pro-TNF; IGFBP-3; IGFBP-5; casein; gelatin; myelin basic protein; pro-MMP2 and pro-MMP9. A significant function of MMP-1 is the degradation of fibrillar collagens in extracellular matrix remodeling. MMP-1 is expressed in fibroblasts; keratinocytes; endothelial cells; monocytes and macrophages. MMP1 can be divided into a number of distinct domains: a prodomain which is cleaved on activation; a catalytic domain containing the zinc binding site and a short hinge region with a carboxyl terminal domain. MMP1 is part of a cluster of MMP genes which localize to chromosome 11q22.3.MMP1 (24-207) Human Recombinant is a single; glycosylated polypeptide chain containing 190 amino acids and having a molecular mass of 21.2kDa. MMP1 (24-207) is fused to a 6 a.a C-terminal His tag.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Assay Kits:MMP
- Datenblatt des Herstellers:download_pdf.php