MMP1 Human; sf9
Produktgrößen
2 µg
£452,00
32-6846-2UG
10 µg
£528,00
32-6846-10UG
Über dieses Produkt
- SKU:
- 32-6846
- Zusätzliche Namen:
- Matrix Metallopeptidase 1; Interstitial Collagenase; Fibroblast Collagenase; EC 3.4.24.7; CLG; Matrix Metalloproteinase 1 (Interstitial Collagenase); Matrix Metallopeptidase 1 (Interstitial Collagenase); Matrix Metalloproteinase 1; Matrix Metalloproteinase-1; Matrix Metalloprotease 1; EC 3.4.24; MM
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.MMP-1 (interstitial collagenase) can break down a wide range of substrates including types I; II; III; VII; VIII; and X collagens as well as L-Selectin; pro-TNF; IL-1 ; IGFBP-3; IGFBP-5; casein; gelatin; 1 antitrypsin; myelin basic protein; pro-MMP2 and pro-MMP9. A significant function of MMP-1 is the degradation of fibrillar collagens in extracellular matrix remodeling. MMP-1 is expressed in fibroblasts; keratinocytes; endothelial cells; monocytes and macrophages. MMP1 can be divided into a number of distinct domains: a prodomain which is cleaved on activation; a catalytic domain containing the zinc binding site and a short hinge region with a carboxyl terminal domain. MMP1 is part of a cluster of MMP genes which localize to chromosome 11q22.3.MMP1 Human Recombinant produced in Sf9 Baculovirus cells is a single; non-glycosylated polypeptide chain containing 460 amino acids (18-469a.a) and having a molecular mass of 53.1kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). MMP1 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Assay Kits:MMP
- Datenblatt des Herstellers:download_pdf.php