GLU-C S.aureus
Produktgrößen
50 µg
£452,00
32-6765-50UG
250 µg
£528,00
32-6765-250UG
Über dieses Produkt
- SKU:
- 32-6765
- Zusätzliche Namen:
- Glutamyl endopeptidase (EC:3.4.21.19); Endoproteinase Glu-C; Staphylococcal serine proteinase; V8 protease; V8 proteinase; sspA.
- Weitere Details:
- Source: Escherichia Coli.Sterile Filtered lyophilized powder.Glutamyl endopeptidase (GLU-C) is an enzyme which cleaves peptide bonds on the carboxyl-terminal side of glutamic acid and; less frequently; aspartic acid (for example: Glu-|-Xaa; Asp-|-Xaa). GLU-C is a pathogenic factor involved in the adherence and colonization of human tissue. GLU-C preferentially cleaves peptide bonds on the carboxyl-terminal side of aspartate and glutamate. GLU-C is required for proteolytic maturation of thiol protease SspB and inactivation of SspC; an inhibitor of SspB. GLU-C is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A; which are involved in adherence to host cells. Furthermore; GLU-C protects bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG; IgA and IgM. GLU-C may also be involved in the stability of secreted lipases.Recombinant Staphylococcal GLU-C produced in E.coli is a single; non-glycosylated polypeptide chain containing a total of 267 amino acids and having a molecular mass of 28.9kDa.
- Aufreinigung:
- Greater than 95% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized GLU-C although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution GLU-C should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php