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Antikörper

CTSD Mouse

Produktgrößen
1 µg
£452,00
32-6710-1UG
5 µg
£528,00
32-6710-5UG
Über dieses Produkt
SKU:
32-6710
Zusätzliche Namen:
Ctsd; CatD; CD; Cathepsin D.
Weitere Details:
Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Cathepsin D is synthesized as a 54kDa precursor; which is proteolytically processed to an intermediate 48kDa single chain; which matures into more stable 34kDa and 14kDa two chain form. It is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane; extracellular matrix; and xonnective tissue. Because of its mitogenic and proteolytic activities; it has been implicated as a prognostic marker in many tumor types. Cathepsin D is expressed in epithelial cells as well as in macrophages.CTSD produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 398 amino acids (21-410 a.a.) and having a molecular mass of 44.0kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). CTSD is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Aufreinigung:
Greater than 90.0% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody