ACE2 Mouse
Produktgrößen
2 µg
£452,00
32-6635-2UG
10 µg
£528,00
32-6635-10UG
Über dieses Produkt
- SKU:
- 32-6635
- Zusätzliche Namen:
- ACE2; 2010305L05Rik; Angiotensin I Converting Enzyme; Angiotensin I Converting; Enzyme (Peptidyl-Dipeptidase A); Angiotensin-Converting Enzyme Homolog; Angiotensin-Converting Enzyme; ACE-Related Carboxypeptidase; Metalloprotease MPROT15; Peptidyl-Dipeptidase A; ACEH; EC 3.4.17.23; EC 3.4.17.
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.ACE-2 (Angiotensin converting enzyme 2) an enzyme bound to cell membranes in various organs such as intestines arteries ; lungs; heart & kidney. ACE2 an entry receptor of SARS coronaviruses as well as SARS-CoV-2;.The coronavirus spike (S) glycoprotein is a class I viral fusion antigen located on the external envelope of the virion that takes part in a critical part in viral infection by identifying host cell receptors and facilitating fusion of the viral and cellular membranes. 2 main domains in coronavirus S1 have been recognized; the N-terminal domain and C-terminal domain. One or the other and/or both S1 domains function as a receptor-binding domain. SARS-CoV + MERS-CoV equally use C-domain to attach their receptors.ACE2 is a type I transmembrane antigen with an extracellular N-terminal domain having the catalytic site and an intracellular C-terminal tail. ACE2 obtains a signal peptide; a transmembrane domain; and a single metalloproteinase active site containing an HEXXH zinc-binding domain. ACE-2 plays a role as a mono-carboxypeptidase which degrades Ang I to produce the nonapeptide Ang 1–9 and Ang II to create the heptapeptide Ang 1–7.ACE2 Mouse produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 731 amino acids (18-740 aa) and having a molecular mass of 84.5kDa. ACE2 is fused to a 6 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php