BCA-1 Mouse
Produktgrößen
5 µg
£452,00
32-6600-5UG
20 µg
£528,00
32-6600-20UG
Über dieses Produkt
- SKU:
- 32-6600
- Zusätzliche Namen:
- C-X-C motif chemokine 13; B lymphocyte chemoattractant; CXC chemokine BLC; Small-inducible cytokine B13; Cxcl13; Blc; Scyb13.
- Weitere Details:
- Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.BCA-1 is a CXC chemokine that is highly expressed in thesecondary lymphoid organs; such as follicles of the spleen; lymph nodes; and Peyer's patches. CXCL13 promotes the migration of B lymphocytes (compared to T cells and macrophages); by stimulating calcium influx into; and chemotaxis of; cells expressing Burkitt's lymphoma receptor 1 (BLR1). BCA1 therefore function in the homing of B lymphocytes to follicles. Human BCA-1 shares a 64% amino acid sequence similarity with the mouse protein and 23 - 34% amino acid sequence identity with other known CXC chemokines. Recombinant or chemically synthesized BCA1 is a potent chemoattractant for B lymphocytes but not T lymphocytes; monocytes or neutrophils. BLR1; a G protein-coupled receptor originally isolated from Burkitt’s lymphoma cells; has now been shown to be the specific receptor for BCA1. Among cells of the hematopoietic lineages; the expression of BLR-1; now designated CXCR-5; is restricted to B lymphocytes and a subpopulation of T helper memory cells.CXCL13 Mouse Recombinant (22-109) produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 88 amino acids and having a molecular mass of 10kDa.The BCA-1 is purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 97.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized BCA1 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution BCA1 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php