TNFRSF10A Human Fc
Produktgrößen
10 µg
£452,00
32-6573-10UG
50 µg
£528,00
32-6573-50UG
Über dieses Produkt
- SKU:
- 32-6573
- Zusätzliche Namen:
- Tumor Necrosis Factor Receptor Superfamily Member 10a; TRAILR1; APO2; DR4; TNF-Related Apoptosis-Inducing Ligand Receptor 1; Death Receptor 4; TRAIL Receptor 1; TRAIL-R1; Tumor Necrosis Factor Receptor Superfamily Member 10a Variant 2; Tumor Necrosis Factor Receptor Superfamily Member 10A; Cytotoxi
- Weitere Details:
- Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.Human TNFRSF10A is a type 1 transmembrane protein in the TNF R superfamily. TNFRSF10A is not expressed in rodents. The trimeric ligand Trail binds TNFRSF10A and induces apoptosis; and recombinant; soluble forms of the receptor inhibit Trail-induced apoptosis. TNFRSF10A is expressed generally in damaged; infected; and malignant cells. TNFRSF10A functions in immune surveillance; inducing apoptosis in cancer cells but not normal cells.TRAIL R1 Fc Human Recombinant (24-240) produced in E.Coli is a non-glycosylated; disulfide-linked homodimer containing two polypeptide chains of 217 amino acids each and having a molecular mass of 41kDa [including tag] each chain. TRAILR1 is fused to a 236 amino acid Fc tag at C-terminal and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized TNFRSF10A although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution TRAIL-R1 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php