Leptin-A Tilapia
Produktgrößen
20 µg
£485,00
32-6484-20UG
100 µg
£644,00
32-6484-100UG
Über dieses Produkt
- SKU:
- 32-6484
- Zusätzliche Namen:
- Leptin is a protein hormone. It is mainly produced in adipose cells that regulate energy homeostasis by restraining hunger. Leptin ties to nuclear receptors in the hypothalamus (arcuate nucleus). Similar to insulin resistance in type II diabetes; in obesity there is a decrease in the sensitivity to
- Weitere Details:
- Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.Leptin is a protein hormone. It is mainly produced in adipose cells that regulate energy homeostasis by restraining hunger. Leptin ties to nuclear receptors in the hypothalamus (arcuate nucleus). Similar to insulin resistance in type II diabetes; in obesity there is a decrease in the sensitivity towards leptin; ending in a failure to identify satiety; even in high levels of energy stores or leptin itself. Full-length cDNA encoding 2 leptin sequences (tLepA and tLepB) and 1 leptin receptor sequence (tLepR) exists in tilapia (Oreochromis niloticus). The full-length cDNA of tLepR is 3423 bp; encoding a protein of 1140 amino acid which contained all functionally important domains conserved among vertebrate leptin receptors. The cDNAs of tLepA and tLepB are 486 bp and 459 bp in length; encoding proteins of 161 aa and 152 aa; respectively. The three-dimensional structures of tLepA and tLepB demonstrates strong conservation of tertiary structure with that of human leptin comprised of 4 helixes.Leptin-A Tilapia Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 161 amino acids and having a molecular mass of 16;491 Dalton. The Leptin-A Tilapia is purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by:(a) Gel filtration analysis.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Leptin-A Tilapia although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Leptin-A Tilapia should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php