IL36A Mouse; His
Produktgrößen
5 µg
£452,00
32-6479-5UG
20 µg
£528,00
32-6479-20UG
Über dieses Produkt
- SKU:
- 32-6479
- Zusätzliche Namen:
- Interleukin-36 alpha; FIL1 epsilon; Interleukin-1 epsilon; IL-1 epsilon; Interleukin-1 family member 6; IL-1F6; Interleukin-1 homolog 1; IL-1H1; Il36a; Fil1e; Il1e; Il1f6; Il1h1.
- Weitere Details:
- Source: E.coli.Sterile Filtered colorless solution.Human IL-36a belongs to the IL-1 family which includes IL-1b; IL-1a; IL-1ra; IL-18; IL-36ra (IL1F5); IL-36b (IL1F8); IL-36g (IL1F9); IL-37 (IL1F7) and IL-38 (IL-1F10). The IL-1 family members display a 12 b-strand; b-trefoil configuration; and are thought to have ascended from a mutual ancestral gene. IL-36a is an 18-22kDa; 158aa intracellular and secreted protein which holds no signal sequence; no prosegment and no potential from N-linked glycosylation sites. IL-36a is released as a reaction to LPS and the cell ATP-induced activation of the P2X7 receptor.Human IL-36a (aa 6-158) shares 57-68% aa sequence homology with mouse; rabbit; equine and bovine IL-36a and 27-57% aa sequence homology with other new IL-1 family members. IL-36a is mostly found in skin and lymphoid tissues; but also in fetal brain; trachea; stomach and intestine.IL36A Mouse Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 183 amino acids (1-160 a.a) and having a molecular mass of 20.4kDa. IL36A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php