EPOR Human; Active

Produktgrößen

2 µg

£452,00

32-6343-2UG

10 µg

£528,00

32-6343-10UG

Über dieses Produkt

SKU:: 32-6343
Zusätzliche Namen:: EPO-R; EPOR; Erythropoietin Receptor.
Weitere Details:: Source: Sf9; Baculovirus cells.Sterile Filtered clear solution.Erythropoietin receptor; also known as EPOR arbitrates erythropoietin-induced erythroblast proliferation as well as differentiation. During EPO binding; EPOR activates Jak2 tyrosine kinase which activates various intracellular pathways including: Ras/MAP kinase; phosphatidylinositol 3-kinase and STAT transcription factors. Furthermore; stimulated EPOR has a function in erythroid cell survival. Mutations in EPOR may possibly produce erythroleukemia and familial erythrocytosis. In addition; dysregulation of EPOR can affect on the growth of selected tumors.EPOR produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 232 amino acids (25-250a.a.) and having a molecular mass of 25.6kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).EPOR is expressed with a 6 amino acid His-tag at C-Terminus and purified by proprietary chromatographic techniques.
Aufreinigung:: Greater than 95.0% as determined by analysis by SDS-PAGE.
Versandbedingungen:: Blue Ice
Lagerbedingungen:: Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Hersteller:: Abeomics
Typ:: Antibodies:Monoclonal Antibody

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