EPOR Human
Produktgrößen
2 µg
£452,00
32-6342-2UG
10 µg
£528,00
32-6342-10UG
Über dieses Produkt
- SKU:
- 32-6342
- Zusätzliche Namen:
- Erythropoietin Receptor; EPO-R; EPOR. Normal 0 false false false EN-US X-NONE HE MicrosoftInternetExplorer4-->
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered clear solution.Erythropoietin receptor; also known as EPOR arbitrates erythropoietin-induced erythroblast proliferation as well as differentiation. During EPO binding; EPOR activates Jak2 tyrosine kinase which activates various intracellular pathways including: Ras/MAP kinase; phosphatidylinositol 3-kinase and STAT transcription factors. Furthermore; stimulated EPOR has a function in erythroid cell survival. Mutations in EPOR may possibly produce erythroleukemia and familial erythrocytosis. In addition; dysregulation of EPOR can affect on the growth of selected tumors.EPOR Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 232 amino acids (25-250 a.a) and having a molecular mass of 25.6kDa. (Migrates at 28-40kDa on SDS-PAGE under reducing conditions). EPOR is fused to an 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php