MERS Spike S1 Recombinant Protein
Produktgrößen
100 µg
£547,00
32-6258-100UG
500 µg
£1030,00
32-6258-500UG
Über dieses Produkt
- SKU:
- 32-6258
- Zusätzliche Namen:
- SARS MERS
- Weitere Details:
- Source : Escherichia Coli. Recombinant SARS MERS Spike S1 is a peptide from amino acids 56-295 of spike protein S1 produced in E. coli and fused to a 6xHis tag at its C-terminus (UniProt accession #AHC74088). SARS MERS is purified by a proprietary chromatographic technique. Since April 2012; cases of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have been identified in the following countries: Saudi Arabia; Qatar; Jordan; the United Arab Emirates; Oman; Kuwait; Yemen; Lebanon; Iran; Algeria; the United Kingdom; France; Italy; Greece; Germany; the Netherlands; Austria; Tunisia; Egypt; Malaysia; Turkey and the United States of America. Coronaviruses are the cause of the common cold; SARS (severe acute respiratory syndrome) and other severe illnesses with high mortality rates; all are classified into coronavirus family. MERS-CoV is a new type of SARS found in the coronavirus family causing severe pneumonia with sudden and serious respiratory illness with high mortality rates as well. Since January 27th 2015; the WHO has reported 956 human cases; including 351 deaths. More cases of the new coronavirus strain are expected. Like in other coronaviruses; large surface spike glycoprotein is a central structural protein of this virus; it is located above the virion surface to bind and enter into the target cell. Spike protein has 2 domains- S1 and S2. The S1 domain is responsible for cellular tropism and interaction with target cell; while the S2 domain is responsible for membrane fusion. The C-terminal of S1 domain contains a receptor binding domain; and is also a potential target for vaccine development and an antigen for diagnosis.
- Aufreinigung:
- Protein is >95% pure as determined by 12% PAGE (coomassie staining).
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php