Recombinant HIV-1 pol Integrase
Produktgrößen
0.5 mg
£1030,00
32-5583-0.5MG
Über dieses Produkt
- SKU:
- 32-5583
- Weitere Details:
- Source : Escherichia Coli. The E.coli derived 36 kDa recombinant protein is a non-glycosylated polypeptide chain; containing the HIV-1 immunodominant regions from the pol protein (intergrase) and fused with a six histidines tag. Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell and is a key component in the pre-integration complex. HIV integrase contains 3 domains; an N-terminal HH-CC zinc fingerdomainwhich is partially responsible for multimerization; a central catalytic domain and a C-terminal domain. Both Central catalytic domain and C-terminal domains have been shown to bind both viral and cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimeror a tetramer. Additionally; several host cellular proteins interact with integrase and may facilitate the integration process.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- HIV-1 Integrase although stable at 4[o]C for 1 week; should be stored below -18[o]C. Please prevent freeze thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg