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Recombinant Human Hepatitis B Virus x Interacting Protein

Produktgrößen
20 µg
£528,00
32-5502-20UG
Über dieses Produkt
SKU:
32-5502
Zusätzliche Namen:
Ragulator complex protein LAMTOR5||Hepatitis B virus X-interacting protein||HBV X-interacting protein||HBX-interacting protein||Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5||LAMTOR5||HBXIP||XIP.
Weitere Details:
Source : Escherichia Coli. HBXIP Human Recombinant produced in E. coli is a single polypeptide chain containing 197 amino acids (aa 1-173) and having a molecular mass of 20.7kDa.HBXIP is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Hepatitis B virus x interacting protein (HBXIP) forms a complex with the C-terminus of hepatitis B virus X (HBX) protein. HBXIP negatively regulates HBX activity and changes the replicative life cycle of the virus. Furthermore; HBXIP is involved in bipolar spindle formation and regulates centrosome dynamics and cytokinesis in cells; possibly due to interaction with Dynein light chain. HBXIP is highly expressed in the skeletal and cardiac muscle; followed by pancreas; kidney; liver; brain; placenta and lung. HBXIP has elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.
Aufreinigung:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Datenblatt des Herstellers:1.jpg