Recombinant Hepatitis C Virus NS4 Mosaic
Produktgrößen
0.5 mg
£1030,00
32-5453-0.5MG
Über dieses Produkt
- SKU:
- 32-5453
- Weitere Details:
- Source : The E.Coli derived 66kDa recombinant HCV NS4 Mosaic protein fused to a His tag is an artificial mosaic polypeptide composite constructed from diagnostically relevant antigenic regions derived from the NS4 region of different HCV genotypes.The protein contains region 5-1-1 and region 59 containing sequence 1789 - 1867 aa and sequence 2322 - 2423 aa of the HCV NS4 genotype lb and 10 other diagnostically relevant antigenic regions derived from the NS4 region of different HCV genotypes. HCV is a small 50nm; enveloped; single-stranded; positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase; the HCV has an exceptionally high mutation rate; a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2; 3; 5 and 6).
- Aufreinigung:
- Protein is >95% pure as determined by 10% PAGE (coomassie staining).
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- HCV NS4 Mosaic although stable at 4[o]C for 1 week; should be stored below -18[o]C. Please prevent freeze thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg