Recombinant Human Heat Shock Protein 105
Produktgrößen
25 µg
£528,00
32-5325-25UG
Über dieses Produkt
- SKU:
- 32-5325
- Zusätzliche Namen:
- HSPH1||Heat Shock protein 105kDa||110kDa protein 1||Heat shock 110 kDa protein||HSP110||HSP105A||Antigen NY-CO-25||HSP105||HSP105A||HSP105B||KIAA0201||NY-CO-25||DKFZp686M05240.
- Weitere Details:
- Source : Escherichia Coli. Recombinant HSPH1 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 894 amino acids and having a molecular mass of 100.9kDa. HSP105 Alpha is fused with a 36 a.a. His tag and purified by conventional chromatography techniques. HSPH1 analysis is used as an indicator and as a diagnostic aid in problematic lesions. HSPH1 chaperones the responses to endoplasmic reticulum (ER) stress during its interactions with GRP78 and GSK3; and without HSP105 cell death following ER stress proceeds by a non-caspase-3-dependent process. HSPH1 is highly expressed in a variety of human tumors.HSPH1 is a mammalian member of the HSP105/110 family; a diverged subgroup of the HSP70 family. HSP105 has 2 isoforms; alpha and beta. Hsp105a associates with Hsp70/Hsc70 as complexes in vivo and regulates the chaperone activity of Hsp70/Hsc70 negatively in vitro and in vivo.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg