Recombinant Human UL16 Binding Protein 3
Produktgrößen
10 µg
£528,00
32-5189-10UG
Über dieses Produkt
- SKU:
- 32-5189
- Zusätzliche Namen:
- UL16 Binding Protein 3||Retinoic Acid Early Transcript 1N||ALCAN-Gamma||NKG2DL3||N2DL-3||RAET1N||UL16-Binding Protein 3||NKG2D Ligand 3||N2DL3||ULBP3.
- Weitere Details:
- Source : Escherichia Coli. ULBP3 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain (Asp30-Gly217) containing 198 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 23.25kDa. UL16 Binding Protein 3 (ULBP3) is a ligand for the NKG2D receptor in NK cells. ULBPs activate different signaling pathways resulting in the production of cytokines and chemokines. ULBP3 is a ligand for the KLRK1/NKG2D receptor; along with at least ULBP1 and ULBP2. Binding of ULBPs ligands to KLRK1/NKG2D stimulates calcium mobilization and activation of the JAK2; STAT5; ERK and PI3K kinase/Akt signal transduction pathway. ULBP3 has lower affinity for KLRK1/NKG2D compared to ULBP1 and ULBP2 and stimulates weaker signaling responses than does ULBP2 or ULBP1.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg