Recombinant Human Tropomyosin-3
Produktgrößen
10 µg
£528,00
32-5111-10UG
Über dieses Produkt
- SKU:
- 32-5111
- Zusätzliche Namen:
- Tropomyosin alpha-3 chain||Gamma-tropomyosin||Tropomyosin-3||Tropomyosin-5||hTM5||TPM3||TM3||TM5||TRK||CFTD||NEM1||TM-5||TM30||TM30nm||TPMsk3||hscp30||OK/SW-cl.5.
- Weitere Details:
- Source : Escherichia Coli. TPM3 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 272 amino acids (1-248 a.a.) and having a molecular mass of 31.6kDa. TPM3 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Tropomyosin alpha-3 chain (TPM3) belongs to the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins which polymerize end-to-end along the major groove in most actin filaments. Tropomyosins give stability to the filaments and regulate access of other actin-binding proteins. In muscle cells; tropomyosins regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy; and oncogenes formed by chromosomal translocations involving this locus are linked with cancer.
- Aufreinigung:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg