Recombinant Human Transcription Elongation Factor B Polypeptide 1
Produktgrößen
20 µg
£528,00
32-5050-20UG
Über dieses Produkt
- SKU:
- 32-5050
- Zusätzliche Namen:
- Transcription elongation factor B polypeptide 1||Elongin 15 kDa subunit||Elongin-C||EloC||RNA polymerase II transcription factor SIII subunit C||SIII p15||TCEB1||SIII.
- Weitere Details:
- Source : Escherichia Coli. TCEB1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 132 amino acids (1-112 a.a.) and having a molecular mass of 14.6kDa. TCEB1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TCEB1 (elongin C) is a subunit of elongin; which is a common transcription elongation factor that increases the RNA polymerase II transcription elongation past template encoded arresting sites. The SIII complex is comprised of elongins A/A2; B and C. The SIII complex activates elongation by RNA polymerase II by curbing transient pausing of the polymerase at numerous sites within transcription units. Elongin A acts as the transcriptionally active component of the SIII complex; while elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis; and able to forming a stable complex with elongins B and C. The VHL (von Hippel-Lindau) tumor suppressor protein binds to elongins B and C; and thus inhibits transcription elongation.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg