Recombinant Human Transcription Elongation Factor A (SII)-Like 7
Produktgrößen
20 µg
£528,00
32-5048-20UG
Über dieses Produkt
- SKU:
- 32-5048
- Zusätzliche Namen:
- Transcription elongation factor A (SII)-like 7||TCEA-like protein 7||transcription elongation factor A protein-like 7||MGC23947||MPMGp800C04260Q003.
- Weitere Details:
- Source : E.coli. TCEAL7 Human Recombinant produced in E. coli is a single polypeptide chain containing 124 amino acids (1-100) and having a molecular mass of 14.8 kDa.TCEAL7 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Transcription Elongation Factor A (SII)-Like 7 (TCEAL7) has a role in the negative regulation of NF-kappa-B signaling at the basal level by controlling transcriptional activity of NF-kappa-B on its target gene promoters. TCEAL7 links with cyclin D1 promoter containing Myc E-box sequence and transcriptionally inhibits cyclin D1 expression. TCEAL7 regulates telomerase reverse transcriptase expression and telomerase activity in both alternative lengthening of telomeres (ALT) and telomerase-positive cell lines. TCEAL7 is highly expressed in normal and fetal brain tissues; and weakly expressed in the uterus and ovary. TCEAL7 is down-regulated in epithelial ovarian; cervical; prostate; breast; brain and lung cancer cell lines and in the brain and ovarian tumors.
- Aufreinigung:
- Greater than 80% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg