Recombinant Human Tubulin Folding Cofactor A
Produktgrößen
25 µg
£528,00
32-5038-25UG
Über dieses Produkt
- SKU:
- 32-5038
- Zusätzliche Namen:
- Tubulin-specific chaperone A||Tubulin-folding cofactor A||CFA||TCP1-chaperonin cofactor A||TBCA.
- Weitere Details:
- Source : Escherichia Coli. TBCA Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 108 amino acids (1-108 a.a.) and having a molecular mass of 12.8 kDa.The TBCA is purified by proprietary chromatographic techniques. TBCA is a tubulin-folding protein which is involved in the early step of the tubulin folding pathway. TBCA is one of four proteins (cofactors A; D; E; and C) implicated in the pathway directing to properly folded beta-tubulin from folding intermediates. Cofactors A and D are thought to be a factor in capturing and stabilizing beta-tubulin in a quasi-native confirmation. TBCA is crucial for cell viability; if reduced it causes a decrease in the amount of soluble tubulin; alterations in microtubules and G1 cell cycle arrest. Cofactor E attaches to the cofactor D-tubulin complex; afterward; interaction with cofactor C triggers the release of tubulin polypeptides that are committed to the native state.
- Aufreinigung:
- Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- TBCA although stable 4[o]C for 4 weeks; should be stored desiccated below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg