Recombinant Human TAR DNA Binding Protein; (1-414 a.a.)
Produktgrößen
20 µg
£528,00
32-5035-20UG
Über dieses Produkt
- SKU:
- 32-5035
- Zusätzliche Namen:
- ALS10; TDP43||TAR DNA-binding protein 43||TDP-43||TARDBP.
- Weitere Details:
- Source : E.coli. TARDBP Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 450 amino acids (1-414 a.a) and having a total molecular mass of 48.8 kDa. TARDBP is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TAR DNA Binding Protein (TARDBP) was initially recognized as a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition; TARDBP has been detected in individuals diagnosed with chronic traumatic encephalopathy as well; which is a condition that often imitates ALS and has been related with athletes who have experienced multiple concussions and other types of head injury.TARDBP has been shown to bind both DNA and RNA; it has multiple functions in transcriptional repression; pre-mRNA splicing and translational regulation.
- Aufreinigung:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg