Recombinant Human Spastic Paraplegia 21
Produktgrößen
20 µg
£528,00
32-4943-20UG
Über dieses Produkt
- SKU:
- 32-4943
- Zusätzliche Namen:
- MAST||ACP33||GL010||BM-019||MASPARDIN||SPG21||Spastic paraplegia 21 autosomal recessive Mast syndrome protein||Acid cluster protein 33.
- Weitere Details:
- Source : Escherichia Coli. SPG21 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 328 amino acids (1-308 a.a.) and having a molecular mass of 94.4 kDa.SPG21 is expressed with a 20 amino acid His tag at N-Terminus and purified by proprietary chromatographic techniques. SPG21 binds to the hydrophobic C-terminal amino acids of CD4 which take part in suppression of CD-4 dependant T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain. SPG21 adapts the stimulatory activity of CD4. SPG21 is broadly expressed in diverse tissues including heart; brain; placenta; lung; liver; skeletal muscle; kidney and pancreas. Mutations in SPG21 cause Mast syndrome; an autosomal-recessive complicated form of hereditary spastic paraplegia characterized by dementia; thin corpus callosum and white matter abnormalities.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg