Recombinant Human Suppressor Of Cytokine Signaling 3
Produktgrößen
10 µg
£528,00
32-4916-10UG
Über dieses Produkt
- SKU:
- 32-4916
- Zusätzliche Namen:
- Suppressor Of Cytokine Signaling 3||CIS3||SSI3||Cytokine-Inducible SH2 Protein 3||STAT-Induced STAT Inhibitor 3||ATOD4||Cish3||MGC71791||CIS-3.
- Weitere Details:
- Source : Escherichia Coli. SOCS3 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 262 amino acids (1-225 a.a) and having a molecular mass of 29kDa.SOCS3 is fused to a 37 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Suppressor of Cytokine Signaling 3; also known as SOCS3 belongs to the SOCS family; in addition SOCS3 is a member of the STAT-induced STAT inhibitor (SSI). The SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of SOCS3 is induced by different cytokines; including IL6; IL10; and interferon (IFN)-gamma. SOCS3 can bind to JAK2 kinase; and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of SOCS3 have shown the roles of SOCS3 in the negative regulation of fetal liver hematopoiesis; and placental development.
- Aufreinigung:
- "Greater than 90% as determined by SDS-PAGE."
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg