Recombinant Human Serpin Peptidase Inhibitor; Clade A Member 8
Produktgrößen
10 µg
£528,00
32-4812-10UG
Über dieses Produkt
- SKU:
- 32-4812
- Zusätzliche Namen:
- Angiotensinogen||Serpin A8||AGT||SERPINA8||ANHU.
- Weitere Details:
- Source : HEK 293. SERPINA8 Human Recombinant produced in HEK cells is a single; glycosylated; polypeptide chain (a.a 34-485) containing a total of 462 amino acids; having a molecular mass of 51.0kDa (calculated) and fused to a 2 a.a C-terminal linker and an 8 a.a Flag tag at C-Terminus.The Human SERPINA8 is purified by proprietary chromatographic techniques. Serpin Peptidase Inhibitor; Clade A Member 8 (SERPINA8); which is a pre-angiotensinogen or angiotensinogen precursor; is expressed in the liver and cleaved by the enzyme renin in response to lowered blood pressure. The ensuing product; angiotensin I; is at that point cleaved by angiotensin converting enzyme (ACE) to produce the physiologically active enzyme angiotensin II. SERPINA8 protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. SERPINA8 gene mutations are linked with susceptibility to essential hypertension; and may cause renal tubular dysgenesis; which is a severe disorder of renal tubular development. Defects in the SERPINA8 gene are also linked with non-familial structural atrial fibrillation; and inflammatory bowel disease.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg