Recombinant Human Mammaglobin-A; HEK
Produktgrößen
10 µg
£528,00
32-4776-10UG
Über dieses Produkt
- SKU:
- 32-4776
- Zusätzliche Namen:
- Mammaglobin-A||Mammaglobin-1||Secretoglobin family 2A member 2||SCGB2A2||MGB1||UGB2||MGC71974.
- Weitere Details:
- Source : HEK 293. Mammaglobin-A Human Recombinant (Fc Chimera) produced in HEK cells is a single; glycosylated; polypeptide chain (Gly19-Phe93) containing a total of 321 amino acids; having a calculated molecular mass of 36.3kDa. The SCGB2A2 protein is fused to a 2 aa C-terminal linker; a 6 aa C-terminal His tag; a 7 aa TEV site and a 231 aa Human IgG1 fragment (Pro100-Lys330). The mammaglobin gene was first identified using a differential screening approach directed at the isolation of novel; human breast cancer-associated genes. Mammaglobin encodes a 10 kDa glycoprotein and is distantly relaetd to a family of epithelial secretory proteins that includes rat estramustine-binding protein/prostatein and human Clara cell 10 kDa protein (CC10)/uteroglobin. Mammaglobin; a mammary-specific member of the uterglobin family; is known to be overexpressed in human breast cancer. Studies suggest that mammaglobin is one of the first relatively mammary-specific and mammary-sensitive markers (85%). Mammaglobin may be valuable used in a panel with BRST-2 (GCDFP-15) and ER in evaluating tumors of unknown primary sites.SCGB2A2 (the mammaglobin gene) is located on chromosome 11; at locus 11q13. SCGB2A2 is member of the secretoglobin superfamily of which is a group of small dimeric secreted and sometimes glycosylated proteins. Expressed mainly in mucosa; secretoglobins appear to be involved in cell signalling; immune response; chemotaxis; and might also serve as transporters for steroid hormones in humans.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg