Recombinant Human Retinoic Acid Receptor Responder 2
Produktgrößen
25 µg
£528,00
32-4608-25UG
Über dieses Produkt
- SKU:
- 32-4608
- Zusätzliche Namen:
- Chemerin||TIG2||Tazarotene-induced gene 2 protein||Retinoic acid receptor responder protein 2||RAR-responsive protein TIG2||RARRES2||HP10433.
- Weitere Details:
- Source : Escherichia Coli. RARRES2 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 138 amino acids and having a total molecular mass of 16 kDa. RARRES2 Human Recombinant is purified by proprietary chromatographic techniques. RARRES2 is a secreted chemotactic protein that initiates chemotaxis through the ChemR23 G protein-coupled seven-transmembrane domain ligand. RARRES2 is upregulated by the synthetic retinoid tazarotene and found in a vast variety of tissues. RARRES2 acts as an adipokine; and is truncated on both termini from the proprotein. RARRES2 is structurally related to the cathelicidin precursors; cystatin C and kininogens. RARRES2 promotes calcium mobilization and chemotaxis of immature dendritic cells and macrophages. RARRES2 is secreted as a precursor of little biological activity; which requires proteolytic cleavage of its COOH-terminal domain to be exchangeed into a potent and highly specific agonist of ChemR23. RARRES2 signals via its receptor; ChemR23 (CMKLR1); as a positive regulator of adipocyte differentiation and metabolic function. The Chemerin receptor acts as a coreceptor for SIV and some primary HIV-1 strains.
- Aufreinigung:
- "Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE."
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Chemerin although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Chemerin should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg