Recombinant Human PIM1
Produktgrößen
10 µg
£528,00
32-4457-10UG
Über dieses Produkt
- SKU:
- 32-4457
- Zusätzliche Namen:
- PIM||Serine/threonine-protein kinase pim-1||PIM1.
- Weitere Details:
- Source : E.coli. PIM1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 274 amino acids (38-290 a.a.) and having a molecular mass of 31.4kDa. PIM1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. PIM1; which is a part of the Ser/Thr protein kinase family and PIM subfamily; is expressed primarily in B-lymphoid and myeloid cell lines; and is overexpressed in hematopoietic malignancies and in prostate cancer. PIM1 functions as Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation; consequently providing a selective advantage in tumorigenesis. Both human and orthologous mouse genes have been reported to encode two isoforms resulting from the use of alternative in-frame translation initiation codons; the upstream non-AUG (CUG) and downstream AUG codons.
- Aufreinigung:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg