Recombinant Human Myeloid Leukemia Factor 1
Produktgrößen
20 µg
£528,00
32-4215-20UG
Über dieses Produkt
- SKU:
- 32-4215
- Zusätzliche Namen:
- Myeloid leukemia factor 1||Myelodysplasia-myeloid leukemia factor 1||MLF1.
- Weitere Details:
- Source : Escherichia Coli. MLF1 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 288 amino acids (1-268 a.a.) and having a molecular mass of 32.8kDa (Molecular weight on SDS-PAGE will appear higher). The MLF1 is purified by proprietary chromatographic techniques. Myeloid leukemia factor 1 (MLF1) is a member of the MLF family; and is a widely expressed negative regulator of cell cycle progression functioning upstream of the tumor suppressor p53. MLF1 hinders the erythropoietin-induced erythroid terminal differentiation by averting cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 generally functions in multi-potent progenitor cells; and its dysregulation may be to some extent responsible for leukemogenesis. Translocations between the MLF1 gene and nucleophosmin are linked to myelodysplastic syndrome and acute myeloid leukemia.
- Aufreinigung:
- Greater than 85.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg