Recombinant Human Methyl-CpG Binding Domain Protein 3
Produktgrößen
10 µg
£528,00
32-4179-10UG
Über dieses Produkt
- SKU:
- 32-4179
- Zusätzliche Namen:
- Methyl-CpG Binding Domain Protein 3||Methyl-CpG-Binding Domain Protein 3||Methyl-CpG-Binding Protein MBD3.
- Weitere Details:
- Source : E.coli. MBD3 Human Recombinant produced in E. coli is a single polypeptide chain containing 314 amino acids (1-291) and having a molecular mass of 35.2 kDa. MBD3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Methyl-CpG-binding domain protein 3 (MBD3); belongs to the MBD family of transcriptional repressors. Human proteins MECP2; MBD1; MBD2; MBD3; and MBD4 includes a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD) in each protein. Nevertheless; not like the other family members; MBD3 is not capable of binding to methylated DNA. MBD3 is a subunit of the NuRD; a multisubunit complex having nucleosome remodeling and histone deacetylase activities. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex.
- Aufreinigung:
- Greater than 85% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg