Recombinant Human Leukocyte-Associated Ig-Like Receptor 1
Produktgrößen
20 µg
£528,00
32-4087-20UG
Über dieses Produkt
- SKU:
- 32-4087
- Zusätzliche Namen:
- Leukocyte-associated immunoglobulin-like receptor 1||LAIR-1||hLAIR1||CD305 antigen||LAIR1||CD305.
- Weitere Details:
- Source : Escherichia Coli. LAIR1 Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing amino acids 105 and having a molecular mass of 11.5 kDa. The extracellular domain of LAIR-1 (22-125aa) was overexpressed in E.coli; and purified by using conventional chromatography techniques. LAIR1 is a glycoprotein (~32kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells; B cells; NK cells; macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells; T cells and B cells. Inhibitory receptors control the immune response to prevent lysis of cells recognized as self. Lair1 consists of a leader sequence; extracellular domain; transmembrane domain; cytoplasmic region. LAIR1 is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. LAIR1 maps to a region of 19q13.4 labeled the leukocyte receptor cluster; which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
- Aufreinigung:
- Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg